Clinical Data
Published data
Tension-Free Vaginal Tape Surgery versus Polyacrylamide Hydrogel Injection for Primary Stress Urinary Incontinence: A Randomized Clinical Trial
Authors: Itkonen Freitas AM , Mentula M , Rahkola-Soisalo P , Tulokas S , Mikkola TS
Published: J Urol. 2020 Feb;203(2):372-378
Link to abstract
"Voice your choice": a study of women's choice of surgery for primary stress urinary incontinence
Authors: Dwyer L , Weaver E , Rajai A , Cox S , Reid F
Published: Int Urogynecol J. 2019 Dec 18
Link to abstract
Particulate Versus Non-Particulate Bulking Agents In The Treatment Of Stress Urinary Incontinence
Authors: Chapple C , Dmochowski R
Published: Res Rep Urol. 2019 Nov 12;11:299-310
Link to abstract
Bulkamid (PAHG) in mixed urinary incontinence: What is the outcome?
Authors: Mohr S , Marthaler C , Imboden S , Monga A , Mueller MD , Kuhn A
Published: Int Urogynecol J. 2017 Nov;28(11):1657-1661
Link to abstract
Current Treatment Concepts for Stress Urinary Incontinence
Authors: Rautenberg O , Zivanovic I , Kociszewski J , Kuszka A , Münst J , Eisele L , Viereck N , Walser C , Gamper M , Viereck V
Published: Praxis (Bern 1994). 2017 Nov 16;106(15):1-8
Link to abstract
Management of recurrent stress urinary incontinence after anti-incontinence surgery
Authors: Martan A , Mašata J , Švabík K
Published: Ceska Gynekol. Winter 2017;82(1):59-64
Transurethral Polyacrylamide Hydrogel Injection Therapy in Women Not Eligible for Midurethral Sling Surgery
Authors: Altman D , Ghilotti F , Bellocco R , Zetterström J , Kopp Kallner H.
Published: Female Pelvic Med Reconstr Surg. 2017 Sep/Oct;23(5):318-323
Link to abstract
Urethral bulking for recurrent stress urinary incontinence after midurethral sling failure
Authors: Zivanovic I , Rautenberg O , Lobodasch K , von Bünau G , Walser C , Viereck V
Published: Neurourol Urodyn. 2017 Mar;36(3):722-726
Link to abstract
Intraurethral bulking agents for the management of female stress urinary incontinence: a systematic review
Authors: Siddiqui ZA , Abboudi H , Crawford R , Shah S
Published: Int Urogynecol J. 2017 Feb 21 [Epub ahead of print]
Link to abstract
A national population-based cohort study of urethral injection therapy for female stress and mixed urinary incontinence: the Danish Urogynaecological Database, 2007-2011
Authors: Hansen MF , Lose G , Kesmodel US , Gradel KO
Published: Int Urogynecol J. 2017 Feb 16 [Epub ahead of print]
Link to abstract
Polyacrylamide hydrogel (Bulkamid®) for stress urinary incontinence in women: a systematic review of the literature
Authors: Kasi AD , Pergialiotis V , Perrea DN , Khunda A , Doumouchtsis SK
Published: Int Urogynecol J. 2016 Mar;27(3):367-75
Link to abstract
Treatment of stress urinary incontinence using polyacrylamide hydrogel in women after radiotherapy: 1-year follow-up
Authors: Krhut J , Martan A , Jurakova M , Nemec D , Masata J , Zvara P
Published: Int Urogynecol J. 2016 Feb;27(2):301-5
Link to abstract
The efficacy and safety of urethral injection therapy for urinary incontinence in women: a systematic review
Authors: Matsuoka PK , Locali RF , Pacetta AM , Baracat EC , Haddad JM
Published: Clinics (Sao Paulo). 2016 Feb;71(2):94-100
Link to abstract
Durability, safety and efficacy of polyacrylamide hydrogel (Bulkamid(®)) in the management of stress and mixed urinary incontinence: three year follow up outcomes
Authors: Pai A , Al-Singary W
Published: Cent European J Urol. 2015;68(4):428-33
Link to abstract
Management of complications in use of urethral bulking agents in women for stress urinary incontinence – a meta-analysis
Authors: Islam M , Wadhwa H , Dobbs R , Kocjancic E
Published: The Journal of Urology; 193 (4), Suppl, 2015, May, Pages e645 (abstract PD28-04)
Link to abstract
Bulking Agents for Stress Incontinence: Are They a Real Option?
Authors: Mock S , Reynolds WS
Published: Current Bladder Dysfunction Reports March 2015, Volume 10, Issue 1, pp46-51
Link to abstract
Transurethral injection of polyacrylamide hydrogel (Bulkamid®) for the treatment of recurrent stress urinary incontinence after failed tape surgery
Authors: Martan A , Mašata J , Švabík K , El-Haddad R , Hubka P , Krhut J
Published: Ceska Gynekol. 2015 Jan;80(1):25-9
Link to abstract
Mixed urinary incontinence: international urogynecological association research and development committee opinion
Authors: Kammerer-Doak D , Rizk DE , Sorinola O , Agur W , Ismail S , Bazi T
Published: Int Urogynecol J. 2014 Oct;25(10):1303-12
Link to abstract
Efficacy and safety of polyacrylamide hydrogel for the treatment of female stress incontinence: a randomized, prospective, multicenter North American study
Authors: Sokol ER , Karram MM , Dmochowski R
Published: J Urol. 2014 Sep;192(3):843-9
Link to abstract
Transurethral injection of polyacrylamide hydrogel (Bulkamid(®)) for the treatment of female stress or mixed urinary incontinence
Authors: Martan A , Masata J , Svabík K , Krhut J
Published: Eur J Obstet Gynecol Reprod Biol. 2014 Jul;178:199-202
Link to abstract
Efficacy of periurethral injections of polyacrylamide hydrogel (Bulkamid(®)) and quality of life of patients with urinary incontinence due to sphincter deficiency (IUE-IS)
Authors: Beraru A , Droupy S , Wagner L , Soustelle L , Muyschondt C , Ben Naoum K , Grés P , Boukaram M , Costa P
Published: Prog Urol. 2014 Jun;24(8):501-10
Link to abstract
Long-term follow-up after urethral injection with polyacrylamide hydrogel for female stress incontinence
Authors: Mouritsen L , Lose G , Møller-Bek K
Published: Acta Obstet Gynecol Scand. 2014 Feb;93(2):209-12
Link to abstract
Use of periurethral injections of polyacrylamide hydrogel for treating post-vesicovaginal fistula closure urinary stress incontinence
Authors: Krause HG , Lussy JP , Goh JT
Published: J Obstet Gynaecol Res. 2014 Feb;40(2):521-5
Link to abstract
Polyacrylamide hydrogel (bulkamid®) in female patients of 80 or more years with urinary incontinence
Authors: Vecchioli-Scaldazza CV , Smaali C , Morosetti C , Azizi B , Giannubilo W , Ferrara V
Published: Int Braz J Urol. 2014 Jan-Feb;40(1):37-43
Link to abstract
Transurethral injection of polyacrylamide hydrogel (Bulkamid®) for the treatment of female stress urinary incontinence and changes in the cure rate over time
Authors: Martan A , Mašata J , Svabík K , El-Haddad R , Hubka P
Published: Ceska Gynekol. 2013 Dec;78(6):554-9
Link to abstract
Treatment of the urethral sphincter insufficiency
Authors: Boissier R , Karsenty G
Published: Prog Urol. 2013 Nov;23(14):1186-92
Link to abstract
Two-year follow-up of an open-label multicenter study of polyacrylamide hydrogel (Bulkamid®) for female stress and stress-predominant mixed incontinence
Authors: Wein AJ
Published: J Urol. 2013 Sep;190(3):974
Link to abstract
Outpatient periurethral injections of polyacrylamide hydrogel for the treatment of female stress urinary incontinence: effectiveness and safety
Authors: Leone Roberti Maggiore U , Alessandri F , Medica M , Gabelli M , Venturini PL , Ferrero S
Published: Arch Gynecol Obstet. 2013 Jul;288(1):131-7
Link to abstract
Bulking agents: an analysis of 500 cases and review of the literature
Authors: Mohr S , Siegenthaler M , Mueller MD , Kuhn A
Published: Int Urogynecol J. 2013 Feb;24(2):241-7
Link to abstract
Periurethral injection of polyacrylamide hydrogel for the treatment of stress urinary incontinence: the impact on female sexual function
Authors: Leone Roberti Maggiore U , Alessandri F , Medica M , Gabelli M , Venturini PL , Ferrero S
Published: J Sex Med. 2012 Dec;9(12):3255-63
Link to abstract
Two-year follow-up of an open-label multicenter study of polyacrylamide hydrogel (Bulkamid®) for female stress and stress-predominant mixed incontinence
Authors: Toozs-Hobson P , Al-Singary W , Fynes M , Tegerstedt G , Lose G
Published: Int Urogynecol J. 2012 Oct;23(10):1373-8
Link to abstract
Periurethral abscess following polyacrylamide hydrogel (Bulkamid) for stress urinary incontinence
Authors: Gopinath D , Smith AR , Reid FM
Published: Int Urogynecol J. 2012 Nov;23(11):1645-8
Link to abstract
Transurethral injection of polyacrylamide hydrogel (Bulkamid) for the treatment of female stress urinary incontinence and changes in the cure rate over time
Authors: Martan A , Masata J , Svabík K , El-Haddad R , Hubka P
Published: Ceska Gynekol. 2011 Dec;76(6):476-81
Link to abstract
Quality of life after periurethral injection with polyacrylamide hydrogel for stress urinary incontinence
Authors: Trutnovsky G , Tamussino K , Greimel E , Bjelic-Radisic V
Published: Int Urogynecol J. 2011 Mar;22(3):353-6
Link to abstract
An open multicenter study of polyacrylamide hydrogel (Bulkamid®) for female stress and mixed urinary incontinence
Authors: Lose G , Sørensen HC , Axelsen SM , Falconer C , Lobodasch K , Safwat T
Published: Int Urogynecol J. 2010 Dec;21(12):1471-7
Link to abstract
Tension-free vaginal tape after failed cystoscopic transurethral injections for stress urinary incontinence
Authors: Altman D , Anzén B , Mörlin B , Falconer C
Published: Scand J Urol Nephrol. 2009;43(6):506-8
Link to abstract
Urethral injection therapy: what is the mechanism of action?
Authors: Klarskov N , Lose G
Published: Neurourol Urodyn. 2008;27(8):789-92
Link to abstract
A new bulking agent (polyacrylamide hydrogel) for treating stress urinary incontinence in women
Authors: Lose G , Mouritsen L , Nielsen JB
Published: BJU Int. 2006 Jul;98(1):100-4
Link to abstract
Ongoing trials
Mixed Urinary Incontinence Symptoms Before and After Treatment With Botox and Bulkamid
Principal investigator: Volker Viereck, MD, Cantonal Hospital, Frauenfeld
Link to clinicaltrials.gov
Estimated study completion date: December 2020
TVT Versus Bulkamid®-Injections in Treatment of Stress Urinary Incontinence
Principal investigator: Tomi Mikkola, Helsinki University Central Hospital
Link to clinicaltrials.gov
Estimated study completion date: December 2022
LATITUDE An Observational Study of Patient Choice and the Urethral Bulking Agent, Bulkamid®
Principal investigator: Fiona M Reid, Manchester University Hospitals NHS Foundation Trust
Link to clinicaltrials.gov
Estimated study completion date: December 2023